Welcome to the Bozec Lab

Our lab uses biophysics and nanometrology to advance the knowledge of human health and disease at the nanoscale.

Explore our research

Explore our research

Translational research group focusing on the application of biophysics and nanometrology to advance the knowledge, understanding and diagnostics of human health and diseases, including oral health.

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Collaborate with us

Collaborate with us

Explore some of our past projects and our approach to collaboration

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View our published research

View our published research

Please find our complete list of publications here

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In November 2013, Isabeth Jefries interviewed Laurent Bozec regarding the future of Atomic Force Microscopy for the next decade. Please read the full account here in Chemistry World.

One of the biggest challenges for AFM is to make the platform more accessible to non-experts,’ comments Laurent Bozec, senior lecturer in biophysics and tissue engineering at the Eastman Dental Institute at University College London in the UK.

Bozec takes a similar view. ‘In future, more AFM settings will be automated and will be more widely available. There will be a simplified version of the instruments but the high end instrument will also be available for research scientists. If the technology can be presented more simply to clinicians, there is no reason why AFM should not move into every UK clinical lab as part of regular medical diagnostics.’

Update – April 2020.

Almost 7 years after this article was written, it is true that AFM as an analytical technique has been developed immensely regarding its ease-of-use. With new modes of operation such as Quantitative Imaging or automatic laser alignment, it is now easy for almost any new users to pick up this technique and obtain data. Understanding what these data means is not yet so accessible and a basic understanding of how AFM works is still required to make the most of the capabilities of this fantastic tool.

The transition to the clinical setting remains a huge unmet challenge. So I guess, we still have a lot to do!

With his former lab at Eastman Dental Institute, University College London (UCL), Dr Bozec was asked by a global leader in skin care, L’Oréal, to investigate the use of novel methods that they were pioneering at the time to characterise collagen properties in skin via a feasibility study.

UCL Researchers look a little deeper into skin ageing, a case study via UCL Consultants, January 25 2018